IL7R anticorps (AA 21-236)
Aperçu rapide pour IL7R anticorps (AA 21-236) (ABIN6654532)
Antigène
Voir toutes IL7R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 21-236
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Purification
- Purified
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Pureté
- Protein G affinity chromatography
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Immunogène
- A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.
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Isotype
- IgG2c kappa
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Indications d'application
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Optimal dilution of the CD127 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
Restrictions
- For Research Use only
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the CD127 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- IL7R (Interleukin 7 Receptor (IL7R))
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Autre désignation
- IL7R / CD127
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Sujet
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
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Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
Antigène
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